scientifyRESEARCH
research funding database

RESEARCH FUNDING

This opportunity is currently closed.

Sign up for Content alerts to stay informed when this or related funding opportunities are posted.

Focused Ultrasound and Blood-Brain Barrier Opening Research Grant (worldwide)

Share this post

Logo of scientifyRESEARCH and Enago "Author First, Quality First" scientifyRESEARCH recommends English editing and author support services from Enago.
Logo of scientifyRESEARCH + logo of Enago "Author First, Quality First" scientifyRESEARCH recommends English editing and author support services from Enago.

The Focused Ultrasound and Blood-Brain Barrier Opening Research Grant (worldwide) from the Focused Ultrasound Foundation and the ALS Association supports research projects that improve the quantification of neurofilament light chain (NfL) in the blood and cerebrospinal fluid, which has emerged as a critical endpoint biomarker for pharmaceutical clinical trials in patients with ALS. Potential projects may include:

  • Investigating the safety of focused ultrasound BBBO in the motor strip by analyzing the kinetics of NfL release into the circulation and effects on motor function.
  • Enhancing our knowledge of biomarker release with focused ultrasound BBBO, including but not limited to proteomics, transcriptomics, and metabolomics.
  • Researching the ability of focused ultrasound BBBO to enhance the delivery of various classes of therapeutics for ALS, including but not limited to, existing approved medications, new antisense oligonucleotides (ASOs), gold nanoparticles, and gene-targeted therapies.

Applicants must hold a faculty appointment as a tenure-track assistant professor or higher rank at award activation. The project must be collaborative and require a team of at least one focused ultrasound researcher and one ALS expert.

The amount of funding available is dependent on the project type:

  • Preclinical research projects will be funded for one to two years with a budget range of $150,000 to $200,000.
  • Clinical research projects will be funded for one to three years (with an option to extend based on patient recruitment) with a budget range of $300,000 to $600,000 dependent upon protocol and number of patients.

Letters of intent are due on October 2, 2023 and invited full applications are due on December 1, 2023.

Full application due:
December 1, 2023

Adverts. Premium members do not see Google Ads.

Please Login / Subscribe to our premium membership to see the content. Sign up to Free trial to see detailed funding information.

non member

Sign-up for our monthly
research funding newsletter

you can unsubscribe at any time

Be the first to know

Sign-up for Personalized Grant Alerts

Logo3