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Ex Vivo Models for Studies at the Intersection of HIV and Poly-Substance Use (USA)

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The Ex Vivo Models for Studies at the Intersection of HIV and Poly-Substance Use (R01 Clinical Trial Not Allowed) funding from the National Institutes of Health (NIH) supports research that addresses neuroimmune and neuronal-glial pathophysiological mechanisms of HIV-associated neurological disorders (HAND) using ex vivo culturing platforms derived from human induced pluripotent stem cells (hiPSC) in the presence of addictive substances. Specific emphasis is on unbiased, reproducible analysis of genetics and epigenetics, neuroglial interactions, and neuroimmune cell activities from the single cell to neural circuit levels. Applications are open to researchers in the USA. Application budgets are not limited but need to reflect the actual needs of the proposed project. The maximum project period is 5 years. 

Opportunity number: RFA-DA-24-001.

Letters of intent are due: July 13, 2023 (optional).

Applications are due: August 13, 2024.

Full application due:
August 13, 2024

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