The Midcareer Investigator Award in Patient-Oriented Research (Parent K24 – Independent Basic Experimental Studies with Humans Required) research funding program from the National Institutes of Health support mid-career health-professional doctorates for protected time to devote to patient-oriented research (POR) and to act as research mentors primarily for clinical residents, clinical fellows and/or junior clinical faculty. This program is for basic science experimental studies involving humans. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should be submitted under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Applicants must have a health-professional doctoral degree. Such degrees include, but are not limited to, the MD, DO, DDS, DMD, OD, DC, PharmD, ND (Doctor of Naturopathy), as well as a doctoral degree in nursing research or practice. Individuals with the PhD or other doctoral degree in clinical disciplines such as clinical psychology, nursing, clinical genetics, speech-language pathology, audiology or rehabilitation are also eligible. Applicants should be mid-career, e.g. Associate Professors. The award provides salary and research expenses for up to 5 years. Opportunity ID: PA-20-192. Applications follow the standard NIH dates for K series grants: February 12, June 12 and October 12. The next applications close on June 12, 2023.