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Tailoring HIV Curative Strategies to the Participant (UM1 Clinical Trial Not Allowed | USA)

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The Tailoring HIV Curative Strategies to the Participant (UM1 Clinical Trial Not Allowed) funding call from the National Institutes of Health (NIH) supports the development of clinical research platforms that will enable future clinical trials to determine whether combinations of HIV cure strategies can be effective when optimally tailored to the participants. The ultimate goal is for the results of such proof-of-concept clinical studies to inform the development and prioritization of more broad-based curative strategies that will be effective in all people living with HIV. Applicants are encouraged to assemble highly collaborative, multidisciplinary teams with expertise in virology, immunology, single-cell analysis, bioinformatics, and clinical research to develop a practical clinical research platform for rapidly and efficiently profiling participants’ intact, rebound-competent HIV reservoirs and their immunologic profiles to provide relevant information needed to design a tailored combination of curative interventions for each participant. Applications are open to researchers based in the USA and from small businesses.

Applicants may apply for up to 2 million USD (plus 8% indirect costs). Projects may span up to 5 years.

Opportunity ID: RFA-AI-24-011

Letters of intent are due June 30, 2024 and full applications are due July 30, 2024.

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