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2024 ADDF-Harrington Scholar Program (Alzheimer’s disease | US, Canada & UK)

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The ADDF-Harrington Scholar Program from the Alzheimer’s Drug Discovery Foundation seeks to advance academic discoveries into medicines for Alzheimer’s disease and related dementias. This funding places high priority on targets related to emerging therapeutic areas for dementia, particularly:

  • Proteostasis (including autophagy, lysosomal biogenesis, proteasomal degradation, post-translational modification associated with proteostasis, protein folding/misfolding, ER stress, extracellular clearance)
  • Senescence (including cells that have halted division, shifted towards a secretory phenotype, altered morphology and epigenetics, and decreased apoptosis)

Other novel targets are encouraged. These include, but are not limited to:

  • Epigenetics
  • Vascular pathology
  • Neuroprotection
  • Synaptic activity and neurotransmitters
  • Inflammation
  • Mitochondrial health
  • Antioxidant defense
  • Metabolic function and brain energy
  • Brain insulin resistance
  • ApoE
  • Glymphatic clearance
  • Postnatal neurogenesis
  • Other aging targets

Applications are open to research teams in the United States, Canada and United Kingdom. Applicants may apply for up to 600,000 USD in funding for a two-year period.
The letter of intent is due June 3, 2024, and the full proposal is due August 26, 2024.

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